MBS673958 | Mouse Anti-Chicken MCAM-BIOT

Mouse Anti-Chicken MCAM-BIOT | MBS673958 | MyBiosource

Product Short Name: [MCAM]

Product Name Synonyme: [Mouse Anti-Chicken MCAM - Biotin; Mouse Anti-Chicken MCAM]

Other Names: [Melanoma cell adhesion molecule; Cell surface glycoprotein MUC18; cell surface glycoprotein MUC18; Gicerin; OTTHUMP00000232151; melanoma adhesion molecule; cell surface glycoprotein P1H12; melanoma-associated antigen A32; melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; melanoma cell adhesion molecule; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [MCAM; MCAM; CD146; MUC18; MUC18]

Clonality: Monoclonal

Isotype: Mouse (BALB/c) IgG2b kappa

Clone: [C264]

Host: Mouse

Reactivity: Chicken

Specificity: Chicken MCAM, Mr 98 kDa (protein core ?84 kDa)
Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.1

Purity: N/A

Form: Biotin (BIOT) Conjugate

Concentration: N/A

Storage Stability: The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.

Tested Application: Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation