Klotho: Biochemical Compounds Declarative Database


Klotho is part of our attempt to model biological processes, beginning with biochemistry. Material on the big questions and some ideas for ways to study them is here. I call the whole project Moirai, after the three Fates of antiquity, since fundamentally these are questions about the fates of molecules and cells. We are grateful for the support of the US NSF (IRI-9117005) and the US NIH (GM/DK56529).

An index:

  • We have modified the manual which contains the Terminals for all the Config Rules declared in Prolog DCG form.


  • What's new on Klotho and Moirai changes, and is worth a look (last revised December 25, 2001).
  • Molecule access:


    • The compound listing is now on a separate page!


    • A table of accession numbers, compound names, and URLs . They're there to be pointed to, so feel free!


  • Computational Mechanics:


    • An explanation of how the compounds are represented and the underlying assumptions .


    • An overview of Moirai and interacting tools .


    • Suggestions on viewing Moirai's pages to best advantage on WWW browsers , including some pointers on configuring your client to use the Chemical MIME type.


    • Klotho is moving into the public domain as rapidly as we can manage it; please see our release statement and rationale for the public domain.
  • Other Forms of Communication:


    • Publications index.


    • If you have any suggestions or corrections, let us know! 
  • Related Stuff for Fun and Contemplation:


    • In addition to the compounds , we've woven together some background material on a variety of topics. To assist in following the several threads, most pages and anchors are color-coded based on their predominant content:
      for biochemistry and computational biology;
      for computer science, software, and the Web;
      for biological engineering;
      for history, linguistics, and classics.


    • Let me know if it's not clear!


  • Finally, you can always get back to this page by clicking this.



What you see is the loving labor of:


  • Brian H. Dunford-Shore
  • Francis Fabrizio
  • Jason Holcomb
  • William Wise
  • Brian Feng
  • Waheeda Sulaman
  • Gaurav Sanghi
  • Toni Kazic


Many thanks to all our helpful colleagues.


Toni Kazic, March 5, 2002