MyBiosource Antibodies
MBS670210 | Rat Anti-Mouse CD54/ICAM-1-APC
- SKU:
- MBS670210
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 0.1 mg
Description
Rat Anti-Mouse CD54/ICAM-1-APC | MBS670210 | MyBiosource
Product Short Name: [CD54/ICAM-1C]
Product Name Synonyme: [Rat Anti-Mouse CD54 (ICAM-1)]
Other Names: N/A
Product Gene Name: N/A
Product Gene Name Synonyme: N/A
Other Gene Names: N/A
Clonality: Monoclonal
Isotype: IgG2b, kappa
Clone: [YN1/1.7.4]
Host: Rat
Reactivity: Mouse
Specificity: Mouse CD54/ICAM-1, Mr 95 kDa
CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-gamma, IL-1, TNF-alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.
Purity: N/A
Form: Allophycocyanin (APC) Conjugate
Concentration: N/A
Storage Stability: The R-phycoerythrin (R-PE) and Allophycocyanin (APC) conjugates are supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Tested Application: Flow Cytometry, Immunohistochemistry (Frozen sections), Immunoprecipitation, In vitro blocking studies 1, Western Blot