MBS670210 | Rat Anti-Mouse CD54/ICAM-1-APC

Rat Anti-Mouse CD54/ICAM-1-APC | MBS670210 | MyBiosource

Product Short Name: [CD54/ICAM-1C]

Product Name Synonyme: [Rat Anti-Mouse CD54 (ICAM-1)]

Other Names: N/A

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [YN1/1.7.4]

Host: Rat

Reactivity: Mouse

Specificity: Mouse CD54/ICAM-1, Mr 95 kDa
CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-gamma, IL-1, TNF-alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.

Purity: N/A

Form: Allophycocyanin (APC) Conjugate

Concentration: N/A

Storage Stability: The R-phycoerythrin (R-PE) and Allophycocyanin (APC) conjugates are supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!

Tested Application: Flow Cytometry, Immunohistochemistry (Frozen sections), Immunoprecipitation, In vitro blocking studies 1, Western Blot