MBS670157 | Mouse Anti-Human TIMP-4-HRP

Mouse Anti-Human TIMP-4-HRP | MBS670157 | MyBiosource

Product Short Name: [TIMP-4]

Product Name Synonyme: [Mouse Anti-Human TIMP-4 - HRP; Mouse Anti-Human TIMP-4]

Other Names: [tissue inhibitor of metalloproteinase-4; tissue inhibitor of metalloproteinase-4]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [TIMP-4]

Clonality: Monoclonal

Isotype: Mouse IgG2a

Clone: [SB30c]

Host: Mouse

Reactivity: Human

Specificity: Human TIMP-4
Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs therefore play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4 (~23kDa), unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation. It has been shown to be an inhibitor of MMP-1, MMP- 2, MMP-3, MMP-7 and MMP-9 with a preference for MMP-2 and MMP-7. 1-9

Purity: N/A

Form: Horseradish Peroxidase (HRP) Conjugate

Concentration: N/A

Storage Stability: The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C.
The horseradish peroxidase (HRP) conjugate is supplied as 1.0 mL of stock solution in 50% glycerol/50% PBS, pH 7.4. No preservative added. Store at 2-8 degree C or long-term at -20 degree C.
Reagents are stable for the period shown on the label if stored as directed.

Tested Application: Immunohistochemistry (Frozen Sections); Western Blot