MBS670015 | Mouse Anti-Cytokeratin 18-HRP

Mouse Anti-Cytokeratin 18-HRP | MBS670015 | MyBiosource

Product Short Name: [Cytokeratin 18]

Product Name Synonyme: [Mouse Anti-Cytokeratin 18 - HRP; Mouse Anti-Cytokeratin 18]

Other Names: [cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [KRT18; KRT18; K18; CYK18; CYK18]

Clonality: Monoclonal

Isotype: Mouse (BALB/c) IgG2b

Clone: [SB38b1]

Host: Mouse

Reactivity: N/A

Specificity: Keratin 18 (48 kDa)1
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology.2-6 Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein of approximately 48 kDa. It exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia, and is often co-expressed with cytokeratin 8.7-9 Tissues from the gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. The SB38b monoclonal antibody reacts specifically with keratin 18 and recombinant N-terminal keratin 18.

Purity: N/A

Form: Horseradish Peroxidase (HRP) Conjugate

Concentration: N/A

Storage Stability: The purified (UNLB) antibody is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2; store at 2-8 degree C.
The fluorescein (FITC) conjugate is supplied as 0.1 mg in 0.2 mL PBS/NaN3. Store at 2-8 degree C.
The horseradish peroxidase (HRP) conjugate is supplied as 1.0 mL of stock solution in 50% glycerol/50% PBS, pH 7.4. No preservative added. Store at 2-8 degree C or long-term at -20
The biotin (BIOT) conjugate is supplied as 0.1 mg in 0.2 mL PBS/NaN3. Store at 2-8 degree C.

Tested Application: ELISA; Immunohistochemistry; Western Blot