MBS488460 | Anti-CD40 [A54 scFv]

Anti-CD40 [A54 scFv] | MBS488460 | Mybiosource

Product Short Name: [CD40]

Product Name Synonyme: [TNFRSF5; A54; Tumor necrosis factor receptor superfamily member 5; B cell surface antigen CD40; B-cell cell surface antigen CD40; B-cell surface antigen CD40; B cell surface antigen CD40; antigen CD40; CD40 antigen; Bp50; Bp-50; CD40L receptor CDw40]

Other Names: [tumor necrosis factor receptor superfamily member 5 isoform 1; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 molecule; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40]

Product Gene Name: [CD40]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD40; CD40; p50; Bp50; CDW40; TNFRSF5; TNFRSF5]

Clonality: Monoclonal

Isotype: Rabbit IgG lambda

Clone: [A54 scFv]

Host: N/A

Reactivity: Human

Specificity: A54 binds specifically to the D1 domain of CD40 (and can only bind to the intact i.e. non-truncated version of CD40 and when an AD2 peptide tag has not been added) and can recognise CD40 on a B cell line (BJAB). This scFv binds to CD40 (immobilized by amine coupling) with a KD within the range of 40nM. CD40 is a glycoprotein of the TNFR superfamily and is expressed on all mature B cells, dendritic cells, activated monocytes, some endothelial cells and some epithelium including the thymus. CD40 binds to the membrane protein CD154 of the TNF superfamily and this interaction is required for the seconfary immune responses and germinal centre formation.

Purity: Protein A Affinity Purified

Form: PBS with 0.02% Proclin 300.

Concentration: 1mg/ml

Storage Stability: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

Tested Application: ELISA (EIA), Blocking (BL), Activate