MBS488440 | Anti-CD105 [MJ7/18]

Anti-CD105 [MJ7/18] | MBS488440 | Mybiosource

Product Short Name: [CD105]

Product Name Synonyme: [Endoglin; Cell surface MJ7/18 antigen]

Other Names: [endoglin isoform 1; Endoglin; endoglin; endoglin; Cell surface MJ7/18 antigen; CD_antigen: CD105]

Product Gene Name: [CD105]

Product Gene Name Synonyme: N/A

Other Gene Names: [Eng; Eng; Endo; CD105; AI528660; AI662476; S-endoglin; Edg]

Clonality: Monoclonal

Isotype: Rabbit IgG kappa

Clone: [MJ7/18]

Host: N/A

Reactivity: Mouse

Specificity: MJ7/18 binds specifically to mouse CD105. CD105 is a homodimer expressed by vascular endothelial cells. CD105 functions in adhesion and embryonic angiogenesis. CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.

Purity: Protein A Affinity Purified

Form: PBS with 0.02% Proclin 300.

Concentration: 1mg/ml

Storage Stability: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

Tested Application: Flow Cytometry (FC/FACS), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)