MBS488355 | Anti-Lymphotoxin alpha [3F12.2D3]

Anti-Lymphotoxin alpha [3F12.2D3] | MBS488355 | Mybiosource

Product Short Name: [Lymphotoxin alpha]

Product Name Synonyme: [chimeric 3F12; LT; LTalpha3; Tumor necrosis factor beta; Tumor necrosis factor beta; Tumor necrosis factor-beta; tumor necrosis factor-beta; TNF beta; TNF-beta; TNF beta; TNF-beta; Lymphotoxin-alpha; Lymphotoxin alpha]

Other Names: [lymphotoxin-alpha; Lymphotoxin-alpha; lymphotoxin-alpha; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1]

Product Gene Name: [LTalpha]

Product Gene Name Synonyme: N/A

Other Gene Names: [LTA; LTA; LT; TNFB; TNFSF1; TNLG1E; TNFB; TNFSF1; LT-alpha]

Clonality: Monoclonal

Isotype: Rabbit IgG, Kappa

Clone: [3F12.2D3]

Host: N/A

Reactivity: Human

Specificity: 3F12 binds to human LTalpha3 and LTalphabeta (with a KD of ~0.3 nM, determined by BIACORE; ~ 37 pM, determined by ELISA) in both its soluble homotrimeric and membrane heterotrimeric forms. LTalpha belongs to the tumor necrosis factor (TNF) superfamily and is secreted as a homo-trimer (LTalpha3), or is expressed on the cell surface in complex with LTbeta. Lymphotoxin is produced by lymphocytes and in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. LTalpha3 signaling induces target cells to upregulate many chemokines and cytokines in an NFkB-dependent manner.

Purity: Protein A Affinity Purified

Form: N/A

Concentration: 1 mg/ml

Storage Stability: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

Tested Application: Neutralization, ELISA (EIA), Flow Cytometry (FC/FACS), Surface Plasmon Resonance (SPR)