MBS488350 | Anti-Fc gamma receptor III [3G8]

Anti-Fc gamma receptor III [3G8] | MBS488350 | Mybiosource

Product Short Name: [Fc gamma receptor III]

Product Name Synonyme: [CD16; low affinity IgG receptor III; FcgammaRIII; low affinity FcgammaRIII]

Other Names: [Fc-gamma receptor IIIb (CD16); Fc-gamma receptor IIIb (CD16); Fc-gamma receptor IIIb (CD16)]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: Rabbit IgG, Kappa

Clone: [3G8]

Host: N/A

Reactivity: Human, Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, Squirrel Monkey, Sooty Mangabey, Cotton-topped Tamarin, Marmoset

Specificity: 3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).

Purity: Protein A Affinity Purified

Form: N/A

Concentration: 1 mg/ml

Storage Stability: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

Tested Application: Flow Cytometry (FC/FACS), Surface Plasmon Resonance (SPR), Depletion, Immunoprecipitation (IP), Immunohistochemistry (IHC), Block (BL)