MBS439664 | LH-beta (Luteinizing Hormone-beta) Mouse Monoclonal Antibody

LH-beta (Luteinizing Hormone-beta) Mouse Monoclonal Antibody | MBS439664 | MyBiosource

Product Short Name: [LH-beta (Luteinizing Hormone-beta) ]

Product Name Synonyme: [CHORIONIC GONADOTROPIN, BETA POLYPEPTIDE 4 (CGB4); hLHB; Interstitial cell stimulating hormone beta chain; Leutropin; LH-B; LHB; LSH-B; LSH-beta; Luteinizing hormone beta polypeptide; Luteinizing hormone subunit beta; Lutropin beta chain; Lutropin subunit beta ]

Other Names: [lutropin subunit beta; Lutropin subunit beta; lutropin subunit beta; luteinizing hormone beta polypeptide; Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta]

Product Gene Name: [LHB]

Product Gene Name Synonyme: N/A

Other Gene Names: [LHB; LHB; CGB4; HH23; LSH-B; LSH-beta; Lutropin beta chain; LH-B; LSH-B; LSH-beta]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [LHb/1214 ]

Host: Mouse

Reactivity: Human

Specificity: Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties. LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin