MBS439266 | CD50 / ICAM-3 Mouse Monoclonal Antibody

CD50 / ICAM-3 Mouse Monoclonal Antibody | MBS439266 | MyBiosource

Product Short Name: [CD50 / ICAM-3 ]

Product Name Synonyme: [ICAMR; Intercellular adhesion molecule 3 (ICAM3) ]

Other Names: [intercellular adhesion molecule 3 isoform 1; Intercellular adhesion molecule 3; intercellular adhesion molecule 3; intercellular adhesion molecule 3; CDw50; ICAM-R; CD_antigen: CD50]

Product Gene Name: [ICAM3]

Product Gene Name Synonyme: N/A

Other Gene Names: [ICAM3; ICAM3; CD50; CDW50; ICAM-R; ICAM-3]

Clonality: Monoclonal

Isotype: IgG2a, kappa

Clone: [101-1D2 ]

Host: Mouse

Reactivity: Human

Specificity: Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin