MBS439260 | CD11a / Integrin alphaL / LFA-1 alpha Chain Mouse Monoclonal Antibody

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MBS439260
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Description

CD11a / Integrin alphaL / LFA-1 alpha Chain Mouse Monoclonal Antibody | MBS439260 | MyBiosource

Product Short Name: [CD11a / Integrin alphaL / LFA-1 alpha Chain ]

Product Name Synonyme: [Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide; Integrin alpha-L; ITGAL; Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain; LFA 1 alpha (LFA1A); Ly15; Ly21; p180 ]

Other Names: [integrin alpha-L isoform b; Integrin alpha-L; integrin alpha-L; integrin subunit alpha L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD_antigen: CD11a]

Product Gene Name: [ITGAL]

Product Gene Name Synonyme: N/A

Other Gene Names: [ITGAL; ITGAL; CD11A; LFA-1; LFA1A; CD11A; LFA-1A]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [DF1524 ]

Host: Mouse

Reactivity: Human

Specificity: Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies

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