MBS439068 | UACA / Nucling (Nuclear Membrane Marker) Mouse Monoclonal Antibody

UACA / Nucling (Nuclear Membrane Marker) Mouse Monoclonal Antibody | MBS439068 | MyBiosource

Product Short Name: [UACA / Nucling]

Product Name Synonyme: [Nuclear membrane binding protein; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA); NUCLING ]

Other Names: [uveal autoantigen with coiled-coil domains and ankyrin repeats isoform 2; Uveal autoantigen with coiled-coil domains and ankyrin repeats; uveal autoantigen with coiled-coil domains and ankyrin repeats; uveal autoantigen with coiled-coil domains and ankyrin repeats]

Product Gene Name: [UACA]

Product Gene Name Synonyme: N/A

Other Gene Names: [UACA; UACA; NUCLING; KIAA1561]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [UACA/1222 ]

Host: Mouse

Reactivity: Human, Mouse

Specificity: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)