MBS438798 | Heparan Sulfate Proteoglycan (Large) / Perlecan Rat Monoclonal Antibody

Heparan Sulfate Proteoglycan (Large) / Perlecan Rat Monoclonal Antibody | MBS438798 | MyBiosource

Product Short Name: [Heparan Sulfate Proteoglycan (Large) / Perlecan]

Product Name Synonyme: [Heparan sulfate proteoglycan of basement membrane; HSPG; Hspg2; LG3 peptide; Perlecan; PLC; SJS1 ]

Other Names: [basement membrane-specific heparan sulfate proteoglycan core protein isoform a; Basement membrane-specific heparan sulfate proteoglycan core protein; basement membrane-specific heparan sulfate proteoglycan core protein; heparan sulfate proteoglycan 2; Perlecan; PLC]

Product Gene Name: [HSPG2]

Product Gene Name Synonyme: N/A

Other Gene Names: [HSPG2; HSPG2; PLC; SJA; SJS; HSPG; SJS1; PRCAN; HSPG; PLC]

Clonality: Monoclonal

Isotype: IgG2a, kappa

Clone: [A7L6 ]

Host: Rat

Reactivity: Human, Monkey, Cow, Pig, Mouse, Fish. Others not known

Specificity: This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin