MBS438337 | CD35 / CR1 (Follicular Dendritic Cell Marker) Mouse Monoclonal Antibody

CD35 / CR1 (Follicular Dendritic Cell Marker) Mouse Monoclonal Antibody | MBS438337 | MyBiosource

Product Short Name: [CD35 / CR1]

Product Name Synonyme: [C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen ]

Other Names: [complement receptor type 1 isoform F; Complement receptor type 1; complement receptor type 1; complement component 3b/4b receptor 1 (Knops blood group); C3b/C4b receptor; CD_antigen: CD35]

Product Gene Name: [CR1]

Product Gene Name Synonyme: N/A

Other Gene Names: [CR1; CR1; KN; C3BR; C4BR; CD35; C3BR]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [E11 ]

Host: Mouse

Reactivity: Human, Baboon, Cynomolgus Monkey, Rhesus Monkey

Specificity: Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin