MBS4381672 | DBC2/RHOBTB2

DBC2/RHOBTB2 | MBS4381672 | Mybiosource

Product Short Name: [DBC2/RHOBTB2]

Product Name Synonyme: [Deleted in breast cancer 2 gene protein; p83; Rho related BTB domain containing protein 2]

Other Names: [DBC2; Rho-related BTB domain-containing protein 2; rho-related BTB domain-containing protein 2; Rho related BTB domain containing 2; Deleted in breast cancer 2 gene protein; p83]

Product Gene Name: [RHOBTB2]

Product Gene Name Synonyme: N/A

Other Gene Names: [RHOBTB2; RHOBTB2; p83; DBC2; EIEE64; DBC2; KIAA0717]

Clonality: Monoclonal

Isotype: IgG2c, kappa

Clone: [DBC2/3362]

Host: Mouse

Reactivity: Human

Specificity: The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. DBC-2 (deleted in breast cancer 2 gene protein), also known as RHOBTB2 (Rho-related BTB domain-containing protein 2), is a 727 amino acid member of the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. Expressed ubiquitously with highest levels in neural tissue, heart, brain and fetal lung, DBC-2 contains two BTB (POZ) domains through which it may bind to and regulate the function of target proteins, such as CUL-3. Additionally, DBC-2 is thought to function as a regulator of cell cycle and apoptosis events. Under normal conditions, DBC-2 is thought to exhibit tumor suppressor activity. Mutations in the gene encoding DBC-2 are associated with breast cancer, suggesting that mutated DBC-2 may play a role in carcinogenesis.

Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin