MBS4381539 | Kallikrein 5 (KLK5)

Kallikrein 5 (KLK5) | MBS4381539 | Mybiosource

Product Short Name: [Kallikrein 5 (KLK5)]

Product Name Synonyme: [HK5; Kallikrein L2; Kallikrein like protein 2; Kallikrein related peptidase 5; Kallikrein-like protein 2 (KLKL2); Stratum corneum tryptic enzyme (SCTE)]

Other Names: [Kallikrein-5; Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme]

Product Gene Name: [KLK5]

Product Gene Name Synonyme: N/A

Other Gene Names: [KLK5; SCTE; KLK-L2]

Clonality: Monoclonal

Isotype: IgG2c, kappa

Clone: [KLK5/3841]

Host: Mouse

Reactivity: Human

Specificity: Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is still currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein, or HGK-1 and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer identification. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers. KLK5 expression is abundant in skin, mammary gland and testis.

Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin