MBS4381400 | CD8A (Cytotoxic- & Suppressor T-Cell Marker)

CD8A (Cytotoxic- & Suppressor T-Cell Marker) | MBS4381400 | Mybiosource

Product Short Name: [CD8A]

Product Name Synonyme: [CD8 antigen; alpha polypeptide (p32); T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain]

Other Names: [T-cell surface glycoprotein CD8 alpha chain isoform 1; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 alpha chain; CD8a molecule; T-lymphocyte differentiation antigen T8/Leu-2]

Product Gene Name: [CD8A]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD8A; CD8A; CD8; p32; Leu2; MAL]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [C8/468]

Host: Mouse

Reactivity: Human

Specificity: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

Purity: Purified Ab conjugated to CF488

Form: Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.

Concentration: N/A

Storage Stability: Antibody with azide: store at 4 to 8 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF)