MBS4381367 | Sarcomeric Actinin Alpha 2/ACTN2

Sarcomeric Actinin Alpha 2/ACTN2 | MBS4381367 | Mybiosource

Product Short Name: [Sarcomeric Actinin Alpha 2/ACTN2]

Product Name Synonyme: [Actin binding protein; Alpha actinin skeletal muscle, isoform 2; CMD1AA; F-actin cross-linking protein]

Other Names: [alpha-actinin-2 isoform 3; Alpha-actinin-2; alpha-actinin-2; actinin alpha 2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein]

Product Gene Name: [ACTN2]

Product Gene Name Synonyme: N/A

Other Gene Names: [ACTN2; ACTN2; CMH23; CMD1AA]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [ACTN2/3291]

Host: Mouse

Reactivity: Human

Specificity: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin