MBS4381294 | C1QA/Complement C1q A-Chain

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C1QA/Complement C1q A-Chain | MBS4381294 | Mybiosource

Product Short Name: [C1QA/Complement C1q A-Chain]

Product Name Synonyme: [Complement C1q subcomponent subunit A; Complement component 1 q subcomponent alpha polypeptide]

Other Names: [complement C1q subcomponent subunit A; Complement C1q subcomponent subunit A; complement C1q subcomponent subunit A; complement C1q A chain]

Product Gene Name: [C1QA]

Product Gene Name Synonyme: N/A

Other Gene Names: [C1QA; C1QA]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [C1QA/2953]

Host: Mouse

Reactivity: Human

Specificity: C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Western Blot (WB), Immunohistochemistry (IHC) Paraffin

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