MBS4380933 | PAI-RBP1/SERBP1/SERPINE1

PAI-RBP1/SERBP1/SERPINE1 | MBS4380933 | Mybiosource

Product Short Name: [PAI-RBP1/SERBP1/SERPINE1]

Product Name Synonyme: [CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI1 RNA-binding protein 1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1 mRNA binding protein 1]

Other Names: [plasminogen activator inhibitor 1 RNA-binding protein isoform 1; Plasminogen activator inhibitor 1 RNA-binding protein; plasminogen activator inhibitor 1 RNA-binding protein; SERPINE1 mRNA binding protein 1; PAI1 RNA-binding protein 1; PAI-RBP1; SERPINE1 mRNA-binding protein 1]

Product Gene Name: [SERBP1]

Product Gene Name Synonyme: N/A

Other Gene Names: [SERBP1; SERBP1; CGI-55; CHD3IP; HABP4L; PAIRBP1; PAI-RBP1; PAIRBP1; PAI-RBP1]

Clonality: Monoclonal

Isotype: IgG2c, kappa

Clone: [SERBP1/3496]

Host: Mouse

Reactivity: Human

Specificity: PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein), also known as SERBP1 (SERPINE1 mRNA-binding protein 1), CGI-55, CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein), HABP4L or PAI-RBP1, is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterone's antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer, suggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin