MBS4380805 | Topoisomerase (DNA) I, Mitochondrial (TOP1MT)

Topoisomerase (DNA) I, Mitochondrial (TOP1MT) | MBS4380805 | Mybiosource

Product Short Name: [Topoisomerase (DNA) I, Mitochondrial (TOP1MT)]

Product Name Synonyme: [DNA topoisomerase I; TOP1MT; Topoisomerase I mitochondrial; Type IB Topoisomerase]

Other Names: [DNA topoisomerase I, mitochondrial isoform 2; DNA topoisomerase I, mitochondrial; DNA topoisomerase I, mitochondrial; DNA topoisomerase I mitochondrial]

Product Gene Name: [TOP1MT]

Product Gene Name Synonyme: N/A

Other Gene Names: [TOP1MT; TOP1MT; TOP1mt]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [TOP1MT/568]

Host: Mouse

Reactivity: Human

Specificity: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin