MBS4380450 | CD25/ IL2RA (Activated Lymphocyte Marker)

CD25/ IL2RA (Activated Lymphocyte Marker) | MBS4380450 | Mybiosource

Product Short Name: [CD25/ IL2RA]

Product Name Synonyme: [IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR]

Other Names: [interleukin-2 receptor subunit alpha isoform 1; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; interleukin 2 receptor subunit alpha; TAC antigen; p55; CD_antigen: CD25]

Product Gene Name: [CD25]

Product Gene Name Synonyme: [IL2RA]

Other Gene Names: [IL2RA; IL2RA; p55; CD25; IL2R; IMD41; TCGFR; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA]

Clonality: Monoclonal

Isotype: IgG2b

Clone: [IL2RA/2395]

Host: Mouse

Reactivity: Human. Others not tested.

Specificity: Recognizes a protein of 55kDa, identified as CD25.It is expressed on activated T- and B-cells and activated monocytes/macrophages.With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R  chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: N/A

Tested Application: Immunohistochemistry (IHC) Formalin