MBS4380376 | VEGI (Vascular Endothelial Growth Inhibitor)

VEGI (Vascular Endothelial Growth Inhibitor) | MBS4380376 | Mybiosource

Product Short Name: [VEGI (Vascular Endothelial Growth Inhibitor)]

Product Name Synonyme: [TNF ligand-related molecule 1 (TL1A); Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15); Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor (VEGI); VEGI192A]

Other Names: [tumor necrosis factor ligand superfamily member 15 isoform VEGI-192; Tumor necrosis factor ligand superfamily member 15; tumor necrosis factor ligand superfamily member 15; TNF superfamily member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor]

Product Gene Name: [VEGI]

Product Gene Name Synonyme: [TNFSF15]

Other Gene Names: [TNFSF15; TNFSF15; TL1; TL1A; VEGI; TNLG1B; VEGI192A; TL1; VEGI]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [VEGI/1283]

Host: Mouse

Reactivity: Human. Others not known.

Specificity: VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin