MBS4380158 | Plakophilin-1 (PKP1)

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MBS4380158
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Description

Plakophilin-1 (PKP1) | MBS4380158 | Mybiosource

Product Short Name: [Plakophilin-1 (PKP1)]

Product Name Synonyme: [B6P; Band 6 protein; PKP1; Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)]

Other Names: [plakophilin-1 isoform 1b; Plakophilin-1; plakophilin-1; plakophilin 1; Band 6 protein; B6P]

Product Gene Name: [PKP1]

Product Gene Name Synonyme: N/A

Other Gene Names: [PKP1; PKP1; B6P; B6P]

Clonality: Monoclonal

Isotype: IgG1

Clone: [10B2]

Host: Mouse

Reactivity: Human, Mouse. Others not known.

Specificity: Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)

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