MBS4380018 | FOXA1/HNF3A

FOXA1/HNF3A | MBS4380018 | Mybiosource

Product Short Name: [FOXA1/HNF3A]

Product Name Synonyme: [Forkhead box protein A1 (FOXA1); Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A); Transcription factor 3A (TCF-3A or TCF3A)]

Other Names: [hepatocyte nuclear factor 3-alpha; Hepatocyte nuclear factor 3-alpha; hepatocyte nuclear factor 3-alpha; forkhead box A1; Forkhead box protein A1; Transcription factor 3A; TCF-3A]

Product Gene Name: [FOXA1]

Product Gene Name Synonyme: [HNF3A]

Other Gene Names: [FOXA1; FOXA1; HNF3A; TCF3A; HNF3A; TCF3A; HNF-3-alpha; HNF-3A; TCF-3A]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [FOXA1/1241]

Host: Mouse

Reactivity: Human, Rat. Others not known.

Specificity: The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin