MBS4157852 | Anti-Human Thymidylate Synthase Antibody

Anti-Human Thymidylate Synthase Antibody | MBS4157852 | Mybiosource

Product Short Name: [Thymidylate Synthase]

Product Name Synonyme: [Human Thymidylate Synthase]

Other Names: [thymidylate synthase; Thymidylate synthase; thymidylate synthase; thymidylate synthase]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [Tyms; Tyms; Ts; TS; TSase]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Sheep

Reactivity: Human, Mouse Rat

Specificity: This purified IgG fraction is directed against human Thymidylate Synthase and is useful in determining its presence in various assays. Because inhibition of Thymidylate Synthase prevents DNA synthesis and cell proliferation, the enzyme is an important target for cancer chemotherapeutic drugs, specifically the fluoropyrimidine group of antineoplastic drugs used to treat solid tumors. In general, this antibody can detect antigen in a variety of human cells and tissues, as well as bacteria, African green monkey, rat and mouse. Somewhat lower dilutions may be required in some non-human cell lines. Anti-Thymidylate Synthase can detect Thymidylate Synthase by immunochemistry in proliferating cell cultures and tissues but does not stain nonproliferating cells. Normal colon mucosa shows weak staining; however, some colorectal cancer specimens show very strong staining.

Purity: Affinity Purified

Form: Liquid; PBS, pH 7.4 with 0.05% sodium azide.

Concentration: 1ug/ul

Storage Stability: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Tested Application: Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)