MBS245270 | Rat Monoclonal [clone BZ332] (IgG2a) to Human CHEMR23 / CMKLR1

Rat Monoclonal [clone BZ332] (IgG2a) to Human CHEMR23 / CMKLR1 | MBS245270 | MyBiosource

Product Short Name: [CHEMR23 / CMKLR1]

Product Name Synonyme: [Anti-CHEMR23 / CMKLR1 Antibody (N-Terminus, clone BZ332) IHC-plus; CMKLR1; Chemokine receptor-like 1; DEZ; CHEMERINR; Resolvin E1 receptor; RVER1; Chemokine-like receptor 1; ChemR23; G-protein coupled receptor DEZ; Human CHEMR23; CMKLR1]

Other Names: [chemokine-like receptor 1 isoform b; Chemokine-like receptor 1; chemokine-like receptor 1; chemerin receptor; resolvin E1 receptor; chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled receptor ChemR23; orphan G-protein coupled receptor, Dez; chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ]

Product Gene Name: [CHEMR23]

Product Gene Name Synonyme: [CMKLR1]

Other Gene Names: [CMKLR1; CMKLR1; DEZ; RVER1; ChemR23; CHEMERINR; CHEMR23; DEZ]

Clonality: Monoclonal

Isotype: IgG2a

Clone: [BZ332]

Host: Rat

Reactivity: Human

Specificity: Recognizes human serpentine chemokine-like receptor 1 (CMKLR1), a novel chemoattractant receptor, which is also referred to Chem23 or DEZ. CMKLR1 is expressed on plasmacytoid dendritic cells (pDC) in blood but is not expressed on myeloid dendritic cells, lymphocytes, monocytes or granulocytes. Studies show that CMKLR1 is also expressed on dendritic cells, which have been generated in vitro from monocytes. The sole ligand for CMKLR1 is chemerin, a chemoattractant that exists at the mRNA level in a wide range of tissues, and as an inactive proform in serum and plasma. Studies suggest that chemerin, in plasma, is converted into a potent pDC attractant following blood coagulation and may be a process by which pDC's are recruited to sites of bleeding and tissue damage

Purity: Protein G Purified

Form: PBS, pH 7.4, 0.09% sodium azide.

Concentration: 1 mg/ml

Storage Stability: +4 degree C or -20 degree C, Avoid repeated freezing and thawing.

Tested Application: Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)