MBS223624 | GOAT ANTI HUMAN NQO1 (C-TERMINAL)

GOAT ANTI HUMAN NQO1 (C-TERMINAL) | MBS223624 | MyBiosource

Product Short Name: [NQO1]

Product Name Synonyme: N/A

Other Names: [NAD(P)H dehydrogenase; NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase [quinone] 1; DT-diaphorase; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; azoreductase; diaphorase (NADH/NADPH) (cytochrome b-5 reductase); diaphorase-4; dioxin-inducible 1; menadione reductase; phylloquinone reductase; quinone reductase 1; NAD(P)H dehydrogenase, quinone 1; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1]

Product Gene Name: [NQO1]

Product Gene Name Synonyme: N/A

Other Gene Names: [NQO1; NQO1; DTD; QR1; DHQU; DIA4; NMOR1; NMORI; DIA4; NMOR1; DTD; QR1]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: Dog (Expected from Sequence), Mouse (Expected from Sequence), Pig (Expected from Sequence), Rat (Expected from Sequence)

Specificity: This item specifically recognises an epitope within the C-terminal (CT) region of human NQO1 (NAD(P)H:quinone oxidoreductase 1), a cytosolic flavoenzyme and member of the NAD(P)H dehydrogenase (quinone) family, involved in detoxification, which catalyzes the two-electron reduction of quinones to hydroquinones.

NQO1 is expressed in a wide range of tissues and is overexpressed in many human tumours including lung, brain, liver, colon and breast. The ability of NQO1 to bioactivate anti-tumour quinones including mitomycin C and diaziquone, has become a focus area for chemotherapeutic studies. Mutations in the NQO1 gene are associated with an increased risk of certain cancers, and an increased risk of leukaemia has been associated with diminished NQO1 activity and the NQO1 *2 allele.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Western Blot (WB)