MBS223135 | GOAT ANTI HUMAN TRIM5 alpha (N-TERMINAL)

GOAT ANTI HUMAN TRIM5 alpha (N-TERMINAL) | MBS223135 | MyBiosource

Product Short Name: [TRIM5 ALPHA ]

Product Name Synonyme: N/A

Other Names: [tripartite motif-containing protein 5 isoform alpha; Tripartite motif-containing protein 5; tripartite motif-containing protein 5; ring finger protein 88; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif containing 5; RING finger protein 88]

Product Gene Name: [TRIM5 alpha]

Product Gene Name Synonyme: N/A

Other Gene Names: [TRIM5; TRIM5; RNF88; TRIM5alpha; RNF88]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: N/A

Specificity: This item specifically recognises an epitope within the N-terminal (NT) region of human TRIM5alpha, otherwise known as RNF88 (RING finger protein 88), a cytoplasmic protein and member of the TRIM/RBCC family, known to play a vital role in species-specific early defence against retrovirus infection.

Studies suggest that it is the association of TRIM5 with specific retroviral capsid sequences which determines the effectiveness of the defence against infection. For example, in Old World monkeys, TRIM5alpha specifically associates with HIV type 1 (HIV-1), whereas in humans TRIM5alpha is not effective against HIV-1, but can inhibit strains of the murine leukaemia virus (MLV).

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)