MBS222955 | RABBIT ANTI MCM2

RABBIT ANTI MCM2 | MBS222955 | MyBiosource

Product Short Name: [MCM2]

Product Name Synonyme: N/A

Other Names: [DNA replication licensing factor MCM2; DNA replication licensing factor MCM2; DNA replication licensing factor MCM2; MCM2 minichromosome maintenance deficient 2, mitotin; cell devision cycle-like 1; cyclin-like 1; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance protein 2 homolog; nuclear protein BM28; minichromosome maintenance complex component 2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28]

Product Gene Name: [MCM2]

Product Gene Name Synonyme: N/A

Other Gene Names: [MCM2; MCM2; BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN; BM28; CCNL1; CDCL1; KIAA0030]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse (Expected from Sequence), Xenopus

Specificity: This item specifically recognises the nuclear protein MCM2 (mini chromosome maintenance protein 2), a putative DNA replicative helicase and member of the MCM family, critical during the initiation of DNA replication.

During the G1 phase of the cell cycle the MCM proteins, part of the pre-replicative complex which assembles at replication origins, undergo phosphorylation by kinases including cyclin dependent kinase (CDK) and Cdc7/Dbf4 (DDK). Studies have shown that the phosphorylation of MCM2 occurs on multiple sites, namely Ser27, Ser41, Ser53, Ser108 and Ser139 and that phosphorylation results in a conformational change of the complex and activation of the helicase activity.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunoprecipitation (IP), Western Blot (WB)