MBS222885 | RABBIT ANTI HUMAN DAXX

RABBIT ANTI HUMAN DAXX | MBS222885 | MyBiosource

Product Short Name: [DAXX]

Product Name Synonyme: N/A

Other Names: [death domain-associated protein 6 isoform a; Death domain-associated protein 6; death domain-associated protein 6; CENP-C binding protein; ETS1-associated protein 1; Fas-binding protein; death-associated protein 6; fas death domain-associated protein; death-domain associated protein; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated protein]

Product Gene Name: [DAXX]

Product Gene Name Synonyme: N/A

Other Gene Names: [DAXX; DAXX; DAP6; EAP1; BING2; BING2; DAP6; hDaxx; EAP1]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse, Rat

Specificity: This item recognises human Death Domain-Associated Protein 6, a novel Fas binding protein that has been designated DAXX.

DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway.

DAXX is predominantly a nuclear protein, where it acts as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)