MBS222874 | GOAT ANTI HUMAN LEPTIN RECEPTOR

GOAT ANTI HUMAN LEPTIN RECEPTOR | MBS222874 | MyBiosource

Product Short Name: [LEPTIN RECEPTOR]

Product Name Synonyme: N/A

Other Names: [leptin receptor isoform 3; Leptin receptor; leptin receptor; OB receptor; huB219; leptin receptor; HuB219; OB receptor; OB-R; CD_antigen: CD295]

Product Gene Name: [LEPTIN]

Product Gene Name Synonyme: N/A

Other Gene Names: [LEPR; LEPR; OBR; OB-R; CD295; LEP-R; LEPRD; DB; OBR; LEP-R; OB-R]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: Dog (Expected from Sequence)

Specificity: This item is specific for human leptin receptor, designated CD295, a type 1 transmembrane glycoprotein and member of the cytokine receptor family, which binds with high affinity to the adipocyte-specific hormone leptin, an obesity factor which regulates adipose-tissue mass/body weight through hypothalamic effects.

The effects of leptin through binding to the long form of CD295 (LRb), are mediated via the JAK/STAT3 signalling pathway, and are vital for the regulation of the normal physiology of many cells, including food intake, lipid metabolism and energy expenditure. CD295-leptin signalling is also involved in the differential regulation of naive and memory T cell proliferation and promotes the release of pro-inflammatory cytokines, including interferon and interleukin-2.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Western Blot (WB)