MBS222802 | RABBIT ANTI HUMAN CD136

RABBIT ANTI HUMAN CD136 | MBS222802 | MyBiosource

Product Short Name: [CD136]

Product Name Synonyme: N/A

Other Names: [macrophage-stimulating protein receptor isoform 2; Macrophage-stimulating protein receptor; macrophage-stimulating protein receptor; MSP receptor; MST1R variant RON30; MST1R variant RON62; PTK8 protein tyrosine kinase 8; RON variant 21; RON variant E2E3; c-met-related tyrosine kinase; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); p185-Ron; soluble RON variant 1; soluble RON variant 2; soluble RON variant 3; soluble RON variant 4; macrophage stimulating 1 receptor; CDw136; Protein-tyrosine kinase 8; p185-Ron; CD_antigen: CD136Cleaved into the following 2 chains:Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]

Product Gene Name: [CD136]

Product Gene Name Synonyme: N/A

Other Gene Names: [MST1R; MST1R; RON; PTK8; CD136; CDw136; PTK8; RON; MSP receptor]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: N/A

Specificity: This item detects CD136, a receptor tyrosine kinase also known as Macrophage stimulating 1 receptor (MST1R) and RON (Recepteur d'origine nantais). CD136 is a member of the MET proto-oncogene family, and is the receptor for macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival.

CD136 is a disulfide-linked 180kD heterodimer composed of a 40kD alpha chain and a 150kD beta chain, and is mainly expressed in cells of epithelial origin. In immune cells CD136 expression is restricted to certain types of tissue macrophages, and its activation is critical in modulating macrophage activities and preventing an excessive inflammatory response. CD136 is also required for embryonic development.

CD136 expression is significantly altered in several primary human cancers including those of the breast and colon.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5 mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Paraffin*