MyBiosource Antibodies
MBS221351 | GOAT ANTI HUMAN CDKN2A (C-TERMINAL)
- SKU:
- MBS221351
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 0.1 mg
Description
GOAT ANTI HUMAN CDKN2A (C-TERMINAL) | MBS221351 | MyBiosource
Product Short Name: [CDKN2A ]
Product Name Synonyme: N/A
Other Names: [cyclin-dependent kinase inhibitor 2A isoform p16INK4a; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; cyclin-dependent kinase inhibitor 2A; CDK4 inhibitor p16-INK4; CDKN2A; cell cycle negative regulator beta; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); multiple tumor suppressor 1; cyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A]
Product Gene Name: [CDKN2A]
Product Gene Name Synonyme: N/A
Other Gene Names: [CDKN2A; CDKN2A; ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A; CDKN2; MTS1; CDK4I; MTS-1; p16-INK4; p16INK4A]
Clonality: Polyclonal
Isotype: IgG
Clone: N/A
Host: Goat
Reactivity: N/A
Specificity: This item detects an epitope within the C-terminal (CT) region of cyclin-dependent kinase inhibitor 2A (CDKN2A). CDKN2A is a 16kD protein which belongs to the CDKN2 cyclin dependent kinase inhibitor family. It acts as a negative regulator of cell proliferation by interacting strongly with CDK4 and CDK6, thus inhibiting their ability to interact with cyclin D and to phosphorylate the retinoblastoma protein.
CDKN2A is an important tumour suppressor and defects in its production results in tumour formation in a wide range of tissues, including cutaneous malignant melanoma and Li-Fraumeni syndrome.
Purity: N/A
Form: Purified
Purified IgG - liquid
Concentration: IgG concentration 0.5mg/ml
Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Tested Application: ELISA (EIA), Western Blot (WB)