MBS221316 | RABBIT ANTI BAP31

RABBIT ANTI BAP31 | MBS221316 | MyBiosource

Product Short Name: [BAP31]

Product Name Synonyme: N/A

Other Names: [B-cell receptor-associated protein 31 isoform b; B-cell receptor-associated protein 31; B-cell receptor-associated protein 31; 6C6-AG tumor-associated antigen; BCR-associated protein Bap31; p28 Bap31; B-cell receptor-associated protein 31; 6C6-AG tumor-associated antigen; Protein CDM; p28]

Product Gene Name: [BAP31]

Product Gene Name Synonyme: N/A

Other Gene Names: [BCAP31; BCAP31; CDM; DDCH; BAP31; 6C6-AG; DXS1357E; BAP31; DXS1357E; BCR-associated protein 31; Bap31]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse, Rat

Specificity: This item recognises an epitope within the internal region of BAP31 (B cell receptor-associated protein 31), a 28kDa conserved type III integral membrane protein of the Endoplasmic Reticulum (ER), containing two caspase cleavage sites within its cytosolic domain.

BAP31 appears to be a multi-functional ER-associated transport protein which was originally identified through its association with membrane IgD in B lymphocytes. Several proteins have since been shown to associate with BAP31, including the Beta2 integrin receptor CD11b/CD18, and nonmuscle gamma-actin and myosin B heavy chain. BAP31 has become a focus area for apoptosis studies due to its association with Bcl-2 and cleavage by initiator caspases including caspase 1 and 8. Cleavage of BAP31 generates a membrane-integrated p20 fragment which is itself a potent inducer of apoptosis when expressed ectopically.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Paraffin, Western Blot (WB)