MBS219793 | RAT ANTI MOUSE CD253

RAT ANTI MOUSE CD253 | MBS219793 | MyBiosource

Product Short Name: [CD253]

Product Name Synonyme: N/A

Other Names: [tumor necrosis factor ligand superfamily member 10; Tumor necrosis factor ligand superfamily member 10; tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis-inducing ligand; TRAIL/APO2L; tumor necrosis factor (ligand) superfamily, member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD_antigen: CD253]

Product Gene Name: [CD253 ]

Product Gene Name Synonyme: N/A

Other Gene Names: [Tnfsf10; Tnfsf10; TL2; Ly81; Trail; APO-2L; AI448571; A330042I21Rik; Trail; Protein TRAIL]

Clonality: Monoclonal

Isotype: IgG2a

Clone: [N2B2]

Host: Rat

Reactivity: N/A

Specificity: This item recognises mouse CD253, also known as TNF-related apoptosis-inducing ligand or TRAIL, a member of the tumour necrosis factor ligand superfamily. When bound to the death receptors DR4 and DR5 caspase-8-dependent apoptosis is induced. However, CD253 might also be bound by the decoy receptor DcR1 which cannot induce apoptosis, and DcR2 which activates NF-kappa-B.

Clone N2B2 has been reported to block NK cell cytotoxicity in vitro.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Flow cytometry (FC/FACS)