MBS219673 | MOUSE ANTI HUMAN FOLLISTATIN 288

MOUSE ANTI HUMAN FOLLISTATIN 288 | MBS219673 | MyBiosource

Product Short Name: [FOLLISTATIN 288]

Product Name Synonyme: N/A

Other Names: [follistatin isoform FST317; Follistatin; follistatin; activin-binding protein; follistatin isoform FST317; follistatin; Activin-binding protein]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [FST; FST; FS; FS]

Clonality: Monoclonal

Isotype: IgG1

Clone: [17/2]

Host: Mouse

Reactivity: N/A

Specificity: This item recognises human follistatin isoform 288 (FS288).

Follistatin (FST) is a single-chain glycosylated protein of gonadal origin, originally identified as an antagonist of activin and suppressor of follicle stimulating hormone (FSH) synthesis/secretion. Alternative splicing of FST mRNA generates the two isoforms FS315 and FS288, the latter of which is the main cell-surface form and binds with high affinity to surface heparan sulphate proteoglycans, whilst FS315 binds with only low-affinity, and is considered to be the main circulating form of follistatin.

As well as activin, FST interacts with other growth factors such as bone morphogenetic proteins (BMPs) -2, -4 and -7, myostatin, and growth differentiation factor 9 (GDF-9), playing a key role in cellular differentiation/proliferation, embryonic development and tissue repair.

Clone 17/2 has been shown to exhibit 10% cross-reactivity with FS315 in an immunoassay.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)