MBS219570 | HAMSTER ANTI MOUSE CD278

HAMSTER ANTI MOUSE CD278 | MBS219570 | MyBiosource

Product Short Name: [CD278]

Product Name Synonyme: N/A

Other Names: [inducible T-cell costimulator; Inducible T-cell costimulator; inducible T-cell costimulator; activation-inducible lymphocyte immunomediatory molecule; inducible costimulator; inducible T-cell co-stimulator; Activation-inducible lymphocyte immunomediatory molecule; CD_antigen: CD278]

Product Gene Name: [CD278 ]

Product Gene Name Synonyme: N/A

Other Gene Names: [ICOS; ICOS; AILIM; CD278; CVID1; AILIM]

Clonality: Monoclonal

Isotype: IgG

Clone: [C398.4A]

Host: Hamster

Reactivity: Human, Pig, Rat

Specificity: This item recognises CD278, also known as Inducible T cell costimulator or ICOS, a CD28-superfamily costimulatory molecule. It is expressed on activated T cells and resting memory T cells. It enhances all the basic T cell responses to a foreign antigen, namely proliferation, secretion of lymphokines and up-regulation of molecules that mediate cell-cell interaction. It is essential for the efficient interaction between B and T cells and is involved in antibody responses to T cell dependent antigens. It up-regulates the synthesis of interleukin-10, but not interleukin-2 and prevents the apoptosis of pre-activated T cells. Clone C398.4A has been reported to costimulate T cell activation and proliferation in vitro.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP)