MyBiosource Antibodies
MBS219550 | RAT ANTI MOUSE CD254
- SKU:
- MBS219550
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 0.25 mg
Description
RAT ANTI MOUSE CD254 | MBS219550 | MyBiosource
Product Short Name: [CD254]
Product Name Synonyme: N/A
Other Names: [tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11; tumor necrosis factor ligand superfamily member 11; OPG ligand; TNF-related activation-induced cytokine; osteoclast differentiation factor; osteoprotegerin ligand; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor-related activation-induced cytokine; tumor necrosis factor (ligand) superfamily, member 11; Osteoclast differentiation factor; ODF; Osteoprotegerin ligand; OPGL; Receptor activator of nuclear factor kappa-B ligand; RANKL; TNF-related activation-induced cytokine; TRANCE; CD_antigen: CD254Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form]
Product Gene Name: [CD254 ]
Product Gene Name Synonyme: N/A
Other Gene Names: [Tnfsf11; Tnfsf11; ODF; OPG; OPGL; RANKL; Ly109l; Trance; Opgl; Rankl; Trance; ODF; OPGL; RANKL; TRANCE]
Clonality: Monoclonal
Isotype: IgG2a
Clone: [IK22/5]
Host: Rat
Reactivity: N/A
Specificity: This item recognises CD254, otherwise known as Receptor activator of nuclear factor kappa B ligand (RANKL) or TNF-related activation-induced cytokine (TRANCE), a member of the tumour necrosis factor ligand superfamily. CD254 is a cytokine that binds osteoprotegerin or RANK and plays an important role in bone metabolism, where it acts as an osteoclast differentiation and activation factor. Overproduction of CD254 is implicated in a range of degenerative bone diseases.
It is also expressed by T helper cells and augments the ability of dendritic cells to stimulate naïve T cell proliferation. It may play a role in regulating interactions between T cells and dendritic cells and in the regulation of T cell-dependent immune responses.
Clone IK22/5 blocks ligand binding.
Purity: N/A
Form: Purified
Purified IgG - liquid
Concentration: IgG concentration 0.5mg/ml
Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Tested Application: Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)