MBS213729 | MOUSE ANTI HUMAN CD58:RPE

MOUSE ANTI HUMAN CD58:RPE | MBS213729 | MyBiosource

Product Short Name: [CD58]

Product Name Synonyme: N/A

Other Names: [lymphocyte function-associated antigen 3 isoform 2; Lymphocyte function-associated antigen 3; lymphocyte function-associated antigen 3; CD58 antigen, (lymphocyte function-associated antigen 3); surface glycoprotein LFA-3; CD58 molecule; Surface glycoprotein LFA-3; CD_antigen: CD58]

Product Gene Name: [CD58]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3]

Clonality: Monoclonal

Isotype: IgG1

Clone: [MEM-63]

Host: Mouse

Reactivity: N/A

Specificity: CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes[1]. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells [2]. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoletic cells in individuals with paroxysmal nocturnal haemoglobinuria.

Purity: N/A

Form: Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised

Concentration: N/A

Storage Stability: Prior to reconstitution store at 4 degree C. Following reconstitution store at 4 degree C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.

Tested Application: Flow cytometry (FC/FACS)