MyBiosource Antibodies
MBS212790 | RAT ANTI MOUSE CD357
- SKU:
- MBS212790
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 0.1 mg
Description
RAT ANTI MOUSE CD357 | MBS212790 | MyBiosource
Product Short Name: [CD357]
Product Name Synonyme: N/A
Other Names: [tumor necrosis factor receptor superfamily member 18 isoform 1; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily member 18; glucocorticoid-induced TNFR-related protein; tumor necrosis factor receptor superfamily, member 18; Glucocorticoid-induced TNFR-related protein; CD_antigen: CD357]
Product Gene Name: [CD357]
Product Gene Name Synonyme: N/A
Other Gene Names: [Tnfrsf18; Tnfrsf18; AITR; Gitr; Gitr]
Clonality: Monoclonal
Isotype: IgG2b
Clone: [YGITR765]
Host: Rat
Reactivity: N/A
Specificity: This product recognises mouse CD357, also known as glucocorticoid-induced tumour necrosis factor receptor (mGITR) or Tnrfsf18, a member of the tumour necrosis superfamily. Mouse CD357 is predominantly expressed by CD4+/CD25+ T regulatory cells and on CD4+/CD25- cells upon activation.Studies demonstrate that mouse GITR ligand (mGITRL) can bind to CD357 and neutralise the suppressive effects of CD4+CD25+ regulatory T cells. CD357 signalling can also enhance the proliferation of naïve and primed T cells, suggesting a key role for CD357 in the regulation of T cell-mediated immunity.
Purity: N/A
Form: Purified
Purified IgG - liquid
Concentration: IgG concentration 1.0 mg/ml
Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Tested Application: Flow cytometry (FC/FACS)