MBS190076 | BRCA1 Monoclonal Antibody

BRCA1 Monoclonal Antibody | MBS190076 | MyBiosource

Product Short Name: [BRCA1]

Product Name Synonyme: [Anti-BRCA1; BRCA1]

Other Names: [BRCA1; Breast cancer type 1 susceptibility protein; breast cancer type 1 susceptibility protein; OTTHUMP00000212143; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; RING finger protein 53; BRCA1/BRCA2-containing complex, subunit 1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein; breast cancer 1, early onset; RING finger protein 53]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [BRCA1; BRCA1; IRIS; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; RNF53]

Clonality: Monoclonal

Isotype: IgG1 kappa

Clone: N/A

Host: Mouse

Reactivity: N/A

Specificity: Anti-BRCA1 [Murine MAb recognizes full-length BRCA1 and does not recognize the Dexon 11 splice variant.]
This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the delta exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.

Purity: N/A

Form: 100 ug Protein G purified antibody in PBS, pH 7.4

Concentration: N/A

Storage Stability: This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.

Tested Application: Immunoblot, Immunohistochemistry, Immunoprecipitation