MBS847835 | Anti-TIGIT, Rabbit IgG, kappa Antibody

Anti-TIGIT, Rabbit IgG, kappa Antibody | MBS847835 | Mybiosource

Product Short Name: [TIGIT, IgG, kappa]

Product Name Synonyme: [T Cell Immunoreceptor With Ig And ITIM Domains; V-Set And Immunoglobulin Domain Containing Protein 9; V-Set And Transmembrane Domain Containing Protein 3; VSIG9; VSTM3; T Cell Immunoreceptor With Ig And ITIM Domains; Washington University Cell Adhesion Molecule; WUCAM]

Other Names: [T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain-containing protein 3]

Product Gene Name: [TIGIT]

Product Gene Name Synonyme: N/A

Other Gene Names: [Tigit; Tigit; Vstm3]

Clonality: Monoclonal

Isotype: Rabbit IgG, kappa

Clone: [4D4]

Host: Rabbit

Reactivity: Mouse

Specificity: Recombinant monoclonal antibody manufactured using Recombinant Platform with variable regions from the hybridoma 4D4 to detect TIGIT expression in mouse. 4D4 is an agonistic anti-TIGIT antibody, and addition of anti-CD3/anti-CD28 stimulated T cells to plate bound 4D4 is known to inhibit their proliferation. Further, 4D4 has been used in order to identify genes that are downstream of TIGIT signaling in Tregs, as TIGIT engagement might modulate the Treg phenotype in tumor tissue.

Purity: Protein A purification

Form: Colorless liquid. In PBS with 0.02% Proclin 300

Concentration: 1mg/ml

Storage Stability: Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

Tested Application: Agonist, Flow Cytometry (FC/FACS)