MBS670354 | Mouse Anti-Human CD49f-UNLB

Mouse Anti-Human CD49f-UNLB | MBS670354 | MyBiosource

Product Short Name: [CD49f]

Product Name Synonyme: [Mouse Anti-Human CD49f]

Other Names: N/A

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: IgG2b

Clone: [4F10]

Host: Mouse

Reactivity: Human

Specificity: Human CD49f
CD49f is the 150 kDa integrin alpha6 chain which associates noncovalently with the integrin beta1 subunit (CD29) and with the integrin beta4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and alpha6beta4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.1-3

Purity: N/A

Form: Purified (UNLB) Antibody

Concentration: N/A

Storage Stability: The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of phosphate buffered saline containing 0.1% PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C.

Tested Application: Flow Cytometry, I mmunoprecipitation, Immunohistochemistry (Frozen sections)