MBS670297 | Mouse Anti-Chicken CD8a-PE/CY5

Mouse Anti-Chicken CD8a-PE/CY5 | MBS670297 | MyBiosource

Product Short Name: [CD8a-PE/CY5]

Product Name Synonyme: [Mouse Anti-Chicken CD8alpha]

Other Names: N/A

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [CT-8]

Host: Mouse

Reactivity: Chicken

Specificity: alpha chain (34-kDa) of chicken CD8
In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8alpha- and CD8beta-chains, a relatively large proportion of the CD8+ TCR-gammadelta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR-gammadelta CD8alphabeta cells in the chicken that is not found in rodents.1,3 Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1,2 MAb CT-8 recognizes the CD8alpha chain.1

Purity: N/A

Form: Spectral Red (SPRD) Conjugate

Concentration: N/A

Storage Stability: The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!

Tested Application: Identification and enumeration of CD8+cells by Flow Cytometry 2, Identification of CD8+ T cells in acetone-fixed, Frozen tissue sections4, Immunoprecipitation 2