MBS670222 | Mouse Anti-Human IL-21-BIOT

Mouse Anti-Human IL-21-BIOT | MBS670222 | MyBiosource

Product Short Name: [IL-21]

Product Name Synonyme: [Mouse anti-Human Interleukin-21 (IL-21)]

Other Names: [interleukin-21 isoform 2; Interleukin-21; interleukin-21; interleukin-21 isoform; interleukin 21; Za11]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [IL21; IL21; Za11; IL-21; IL-21]

Clonality: Monoclonal

Isotype: IgG2a

Clone: [SB134f]

Host: Mouse

Reactivity: Human

Specificity: Reacts with human IL-21
Interleukin-21 (IL-21) is a four helical bundle type I cytokine1. The mature form of human IL-21 is a 131 amino acid protein.4 IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells and augmentation of antitumor activity of CD8+ T cells.2, 3 Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. Clone SB134f can be used as a detection antibody for sandwich ELISA.5

Purity: N/A

Form: Biotin (BIOT) Conjugate

Concentration: N/A

Storage Stability: The biotin (BIOT) conjugate is supplied as 0.5mg labeled antibody in 1.0mL of PBS/NaN3. Store at 2-8 degree C.
Reagents are stable for the period shown on the label if stored as directed.

Tested Application: ELISA