MBS670218 | Mouse Anti-Human IL-31-BIOT

Mouse Anti-Human IL-31-BIOT | MBS670218 | MyBiosource

Product Short Name: [IL-31]

Product Name Synonyme: [Mouse anti-Human Interleukin-31 (IL-31)]

Other Names: [interleukin-31; Interleukin-31; interleukin-31; interleukin 31]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [IL31; IL31; IL-31; IL-31]

Clonality: Monoclonal

Isotype: IgG2b

Clone: [SB118b1]

Host: Mouse

Reactivity: Human

Specificity: Reacts with native and recombinant human IL-311
Interleukin-31 (IL-31) is a 24kD alpha-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells2. This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a broad range of immune and non-immune cells, IL-31 binding can induce activation of the Jak/STAT, AKT and MAPK signaling pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles that include regulating hematopoiesis and immune response3,4. Over-expression has been linked chronic inflammatory states such as dermatitis, pruritus, airway hypersensitivity and inflammatory bowel disease5-7.

Purity: N/A

Form: Biotin (BIOT) Conjugate

Concentration: N/A

Storage Stability: The biotin (BIOT) conjugate is supplied as 0.5mg labeled antibody in 0.2mL of PBS/NaN3. Store at 2-8 degree C.

Tested Application: ELISA