MBS670189 | Mouse Anti-Human IL-33-UNLB

Mouse Anti-Human IL-33-UNLB | MBS670189 | MyBiosource

Product Short Name: [IL-33]

Product Name Synonyme: [Mouse Anti-Human Interleukin-33 (IL-33)]

Other Names: [interleukin-33 isoform 3; Interleukin-33; interleukin-33; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules; interleukin 33; Interleukin-1 family member 11; IL-1F11; Nuclear factor from high endothelial venules]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV]

Clonality: Monoclonal

Isotype: IgG2b

Clone: [SB127c1]

Host: Mouse

Reactivity: Human

Specificity: Reacts with human IL-33
Interleukin-33 (IL-33), also known as NF-HEV, is a 30kD protein and a recently identified member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells, but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways2. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-kappaB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5 and IL-133,4. In vivo administration of this cytokine in mice resulted in eosinophilia and splenomegaly, as well as induced severe pathological changes in the lungs, gastrointestinal tract and other mucosal organs3,5,6.

Purity: N/A

Form: Purified (UNLB) Antibody

Concentration: N/A

Storage Stability: The purified (UNLB) antibody is supplied as 0.5mg purified immunoglobulin in 1.0mL of 100mM borate buffered saline, pH 8.2; store at 2-8 degree C.
Reagents are stable for the period shown on the label if stored as directed.

Tested Application: ELISA